Dr. Rajendra H.  Amilkanthwar
M.D. (Shalya) Ph.D. (Scholar)
 

Urethral Stricture:

Modern Aspect:

Etiology :

Urethral stricture divided into two varieties:
 

A. Congenital :

1.    Urethral Stenosis : Distensibility of urethral wall is reduced or it may be due decreased laxity of paraurethral tissues.

2.    Meatal Stenosis :

B. Traumatic :

1.    Rupture of bulbous urethra due to RTA

2.    Rupture of membranous urethra (Intrapelvic rupture), rupture of pelvis and Rupture of bladder.

C. Inflammatory :
1.    Post gonorrhoreal :- Urethritis

2.    Post gonorrhoreal chancre – primary syphilitic chancre at meatus usually head with fibrosis resulting in meatal stenosis.

3.    Non specific infections : may spread from bladder or during catheterization, cystoscopy or surgery

4.    Instrumental :

a.    Indwelling catheter repeated and prolonged catheter necessary in post operative cases and motor dysfunction may cause repeated friction of the mucosa carry urethritis causes stricture.

b.    Endoscopy : Following caliber of large endoscope notably a resectoscope causes stricture.

c.     Post prostatectomy : Post operative bladder neck stenosis.

d.    Amputation of penis : post amputation scarring of remaining urethra and periurethral tissues.

 

Pathogenesis :

1.    Partial loss of uroepithelial lining.

2.    After dilatation and internal urethrotomy – base areas are created slow epithelial proliferation cleft closure and spongiofibrosis result in a tendency to restenosis.

Post gonorrhoreal stricture :

                                                                                              

 

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Clinical Features :

1.    Passage of flakes (desquamated epithelium) in urine.

2.    Urethral discharge at early morning.

3.    Dysurea

4.    Straining

5.    prolonged micturition

6.    Dribbling occur due urine trickling from dilated urethra above stricture.

7.    Frequency of micturition is increased at day and night

8.    Possible to palpate the stricture from outside as an induration in the urethral floor.

9.    Burning micturition

10.  Occasionally haematuria secondary to localized inflammatory changes instrumentation and passage of calculi

11.  Retention of urine

12.  Incontinence of urine

13.  Strangury

14.  Decreased stream of micturition.

 

Effect of Urethral Stricture :

1. On Urethra :

            Urethra above the stricture may get dilated or diverticulum may be found due to increased pressure from bladder due to straining.

 

2. On Bladder :

  • Musculature of bladder is hypertrophied

  • Trabeculation and divertiulum may be found

  • Calculi are prone to form in stagnant pool and residual urine

  • Long standing cases bladder atony may occur

3. On Ureter and Kidney :

  • Bil. Hydronephrosis

  • Chr. Interstitital nephritis due to back pressure

  • Acute or chr. Pyelonepritis

4. On Sexual Organ :

  • Seminal vesiculits

  • Prostatitis

  • Orchitis

 

Effect of Straining:

            Herniation, haemorrhoids, prolapse etc.  

Diagnosis:

A) Routine Investigation

1. Blood for HB, TLC, DLC, ESR, V DRL

2. Urine Routine

3. X ray KUB

4. Urodynamic study / volumetric study.

B) Specific Investigations

1. Kidney function test

2. Urine culture and sensitivity.

3. IVP

4. Retrograde urethrography

5. Cystoscopy

 

Retrograde Urethrography :

It is helpful to confirm the diagnosis -

1.    localize the lesion

2.    understand the extent and nature of stricture

3.    for comparison between before and after treatment  

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Ayurvedic Aspect :

Causes (Etiology)

1.    Drinking water or eating when the bladder is full and urge to pass urine is present.

2.    Suppressing micturition

3.    Excessive indulgence in intercourse

4.    Exhaustion and injury lead to diseases of urinary bladder.

5.    Akalyonigamana, Ayonigamana, Mastrubation

6.    Forceful control of sexual desire, extensive sexual practice and trauma to reproductive organ by means of surgery i.e. shashtra, kshar and Agni

7.    Dhwajbhanga (extragenital intercourse, intercourse with a lady having vaginal, gynaecological disorder, who has not done intercourse since long period of time, during menstruation)  

 

Shushruta Described Urinary Tract Disorder of Two Type :

1)    Mutraghat

2)    Mutrakruchra

1) Mutraghat : Obstruction to passage of urine -  12 types

1)    Vatkundalika                   2)    Vatashtila                         3)    Vatbasti

4)    Mutrateet                          5)    Mutrajathar                      6)    Mutrotsang

7)    Mutrakshya                      8)    Mutragranthi                   9)    Mutrashukra

10)  Ushanvat                        11)  Pittajmutrotsad              12)    Kaphajmutrotsad

 

Mutrakrichra :

Obstruction to urine is much or less but micturition is usually associated with pain, burning and difficulty.

Type :

A)    Vataj                                           B)    Pittaj                                  C)    Kaphaj

D)   Sannipataj                                 E)    Abhighataj                        F)    Ashmarij

G)   Sharkaraj                                   H)    Shakrut

 

Mutramarga Sankoch (Lakshana - Sign and Symptoms) 

a.    Difficult, frequent, painful, prolonged micturition with straining with little amount of urine

b.    Sign of retention of urine

c.     Pain in lower abdomen, flank, scrotum, perineum

d.    Haematuria

e.     Physical appearance of urine change dark, yellowish, reddish.

f.     Stream of Urine is either thin or bifurcated.

 

Samprapti of Mutramarga Sankoch (Pathogenesis)

According to Charaka, the basti is vatsthana an apan vayu is seated at testicles, bladder, guda, penis etc. and responsible for normal evacuation of bladder, bowel, and ejaculation. The diseases occurring in this region are mainly due to vat dusthi.

Increase in khar, Ruksha guna responsible for local constriction and hardening of tissues leading to constriction of urethra. Increase in chala guna leading to frequent micturition and cause pain. When vayu get stage of prakopa it causes mutra sanga, tod (thrombing pain), Sankoch (Stricture), shosha and shoola.

            Kapha prakop is manifested with sthairya as local stasis, gaurav as heaviness in penis in mutrosanga, uplepa (narrowing of lumen) due to hypertrophied scar tissues, bandha (obstruction to normal flow) chirkaritwa (chronicity)

            Hence combination of Vat +++ and kapha + is causative factor doshas behind the mutramarga sanchoch i.e. urethral stricture.

            Urethral passage is lined by mucosa which is shleshmadharakala / internal lining which may be considered as updhatu of Mansa. It gets affected and diseased mucosa promoted the disease to submucosal structure and their involvement lead to stricture. Twachas is updhatu of Mansa which is nourished by Rasa and Rakta hence in this disease Rasa Rakta, Mansa are affected Dhatus.

            Mutravaha strotas is involved hence Mutra is among the dushyas. As Mutra prasek is common pathway for Mutra and Shukra in male so Shukra is also involved in this disease.

Dosh Dushya Samurchana of Mutramarga Sankoch

Dosha              Vat                  + + +

   Kapha              +

Dhusyas          Dhatu          - Ras

- Rakta

- Mansa – Twacha

- Shukra

   Mala             - Mutra.

 

Sadhya Sadhyatwa (Prognosis) :

  • Mutra Marga Sankoch (Urethral Stricture)- Yapya vyadhi

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